Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18323618 | 0.84 | KDM4E (0.55) | KDM4EKMT2AGLABRD4TSHR | |
| SCHEMBL10377918 | 0.83 | KDM4E (0.41) | KDM4ETPMTNR4A1MEN1KMT2A | |
| SCHEMBL18323588 | 0.81 | KDM4E (0.51) | KDM4EKMT2ATDP1POLBALDH1A1 | |
| SCHEMBL18323576 | 0.80 | PDE8A (0.38) | KDM4ETPMTNR4A1MEN1KMT2A | |
| SCHEMBL18323585 | 0.80 | KDM5A (0.41) | KDM4ETPMTNR4A1MEN1KMT2A | |
| SCHEMBL18323694 | 0.80 | KDM4E (0.39) | KDM4ETPMTNR4A1MEN1KMT2A | |
| SCHEMBL18323689 | 0.80 | KDM4E (0.39) | KDM4ETPMTNR4A1MEN1KMT2A | |
| SCHEMBL15907105 | 0.80 | MEN1 (0.37) | KDM4ETPMTNR4A1MEN1KMT2A | |
| SCHEMBL18323584 | 0.78 | TPMT (0.38) | KDM4ETPMTNR4A1MEN1KMT2A | |
| SCHEMBL18323580 | 0.78 | KDM4E (0.37) | KDM4ETPMTNR4A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9522910-B2 | Protein kinase inhibitors (variants), use thereof in treating oncological diseases and a pharmaceutical composition based thereon | Obshchestvo s ogranichennoy otvetstvennostyou “Fusion Pharma” (RU) | 2016-12-20 | — | — | US | disclosed |