Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937892 | 0.83 | HDAC1 (1.00) | HDAC3HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL2225861 | 0.71 | HDAC6 (1.00) | HDAC3HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL6882831 | 0.69 | HDAC6 (1.00) | HDAC3HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL2225154 | 0.68 | HDAC6 (0.69) | HDAC3HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL2227746 | 0.67 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL2225157 | 0.67 | HDAC6 (0.66) | HDAC3HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL6881257 | 0.67 | HDAC6 (1.00) | HDAC3HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL19997023 | 0.66 | HTR7 (0.54) | HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL15480431 | 0.66 | POLB (0.66) | HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL18324086 | 0.66 | HDAC3 (0.52) | HDAC3HDAC1HDAC6HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2330894-B1 | COMPOSITIONS INCLUDING 6-AMINOHEXANOIC ACID DERIVATIVES AS HDAC INHIBITORS | REPLIGEN CORP (US) | 2016-12-21 | — | — | EP | disclosed |