Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283760 | 0.96 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2RECQLL3MBTL1KDM4E | |
| SCHEMBL28377075 | 0.87 | TLR8 (0.62) | ALDH1A1SMN1; SMN2RECQLL3MBTL1KDM4E | |
| SCHEMBL14648254 | 0.87 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2RECQLL3MBTL1KDM4E | |
| SCHEMBL3619365 | 0.84 | MAPK1 (0.61) | ALDH1A1SMN1; SMN2RECQLL3MBTL1KDM4E | |
| SCHEMBL27847996 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2RECQLL3MBTL1KDM4E | |
| SCHEMBL28378028 | 0.83 | TLR8 (0.63) | ALDH1A1SMN1; SMN2RECQLL3MBTL1KDM4E | |
| SCHEMBL28372897 | 0.82 | TLR8 (0.64) | ALDH1A1SMN1; SMN2RECQLTSHRNPSR1 | |
| SCHEMBL28373626 | 0.82 | TLR8 (0.64) | ALDH1A1SMN1; SMN2RECQLTSHRNPSR1 | |
| SCHEMBL28378368 | 0.82 | TLR8 (0.64) | ALDH1A1SMN1; SMN2RECQLTSHRNPSR1 | |
| SCHEMBL30497266 | 0.81 | HPGD (0.62) | ALDH1A1SMN1; SMN2RECQLKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327735-B1 | METHOD FOR PREPARING POLYLACTIC ACID AND PRODUCTS THEREOF USING A TWIN-SCREW EXTRUDER | NANJING UNIV OF TECH (CN) | 2016-12-21 | — | — | EP | disclosed |