SCHEMBL1832479

SCHEMBL1832479

CCc1ccc(C=C(C#N)C(=O)O)cc1.[c]1ccccc1

nearest known ligand 0.83

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.56
ALDH1A1 P00352 2/20 0.56
HPGD P15428 2/20 0.56
KMT2A Q03164 1/20 0.56
CISD1 Q9NZ45 1/20 0.55
SLC16A3 O15427 1/20 0.55
CYP3A4 P08684 1/20 0.55
SLC16A1 P53985 1/20 0.55
GPR35 Q9HC97 1/20 0.55
EGFR P00533 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9362275 0.91 KDM4E (0.65) KDM4EALDH1A1HPGDKMT2ACISD1
SCHEMBL9362272 0.91 KDM4E (0.65) KDM4EALDH1A1HPGDKMT2ACISD1
SCHEMBL3133118 0.84 KDM4E (0.62) KDM4EALDH1A1HPGDCISD1SLC16A3
SCHEMBL3411261 0.80 CISD1 (0.43) KDM4EALDH1A1HPGDCISD1SLC16A3
SCHEMBL9365790 0.80 CISD1 (0.61) KDM4EALDH1A1HPGDCISD1SLC16A3
SCHEMBL9365799 0.80 CISD1 (0.61) KDM4EALDH1A1HPGDCISD1SLC16A3
SCHEMBL4600830 0.78 EGFR (0.85) KDM4EALDH1A1HPGDCISD1SLC16A3
SCHEMBL4600832 0.78 EGFR (0.85) KDM4EALDH1A1HPGDCISD1SLC16A3
SCHEMBL10413058 0.78 EGFR (0.85) KDM4EALDH1A1HPGDCISD1SLC16A3
SCHEMBL28862320 0.78 EGFR (0.68) KDM4EALDH1A1HPGDKMT2ACISD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2565238-B1 METALLIC-PIGMENT COMPOSITION ASAHI CHEMICAL IND (JP) 2017-08-23 EP disclosed
EP-2581419-B1 METALLIC PIGMENT COMPOSITION ASAHI KASEI CHEMICALS CORP (JP) 2016-10-05 EP disclosed
US-9296906-B2 Metallic pigment composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-03-29 US disclosed
US-8871833-B2 Metallic-pigment composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-10-28 US disclosed
US-20130101813-A1 METALLIC-PIGMENT COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-04-25 US disclosed
EP-2581419-A1 METALLIC PIGMENT COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2013-04-17 EP disclosed
US-20130078438-A1 METALLIC PIGMENT COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-03-28 US disclosed
EP-2565238-A1 METALLIC-PIGMENT COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2013-03-06 EP disclosed
EP-2554608-A1 METALLIC PIGMENT COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2013-02-06 EP disclosed
US-20130011639-A1 METALLIC PIGMENT COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-01-10 US disclosed
EP-1275668-B1 PHOTOCURABLE COMPOSITION, CURED OBJECT, AND PROCESS FOR PRODUCING THE SAME MITSUBISHI CHEM CORP (JP) 2011-05-11 EP disclosed
US-6759104-B2 LIQUID CRYSTALS DISPLAY; MIXTURE CONTAINING ACRYLATED ESTERS; PHOTOPOLYMERIZATION USING FREE RADICAL CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2004-07-06 US disclosed
US-20030118941-A1 Photocurable composition, cured product and process for producing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2003-06-26 US disclosed