SCHEMBL3133118

SCHEMBL3133118

N#CC(=Cc1ccccc1)C(=O)O.[c]1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.62
EGFR P00533 2/20 0.62
MCL1 Q07820 1/20 0.62
CISD1 Q9NZ45 1/20 0.62
SLC16A3 O15427 1/20 0.62
ALDH1A1 P00352 1/20 0.62
CYP3A4 P08684 1/20 0.62
HPGD P15428 1/20 0.62
SLC16A1 P53985 1/20 0.62
GPR35 Q9HC97 1/20 0.62
PLIN1 O60240 1/20 0.51
LMNA P02545 1/20 0.51
PLIN5 Q00G26 1/20 0.51
ABHD5 Q8WTS1 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305983 0.91 KDM4E (0.72) KDM4EEGFRMCL1CISD1SLC16A3
SCHEMBL305982 0.91 KDM4E (0.72) KDM4EEGFRMCL1CISD1SLC16A3
SCHEMBL3009380 0.91 KDM4E (0.72) KDM4EEGFRMCL1CISD1SLC16A3
SCHEMBL1832479 0.84 KDM4E (0.56) KDM4EEGFRCISD1SLC16A3ALDH1A1
SCHEMBL4600832 0.83 EGFR (0.85) KDM4EEGFRCISD1SLC16A3ALDH1A1
SCHEMBL10413058 0.83 EGFR (0.85) KDM4EEGFRCISD1SLC16A3ALDH1A1
SCHEMBL4600830 0.83 EGFR (0.85) KDM4EEGFRCISD1SLC16A3ALDH1A1
SCHEMBL8129603 0.81 AKR1C3 (0.70) KDM4EEGFRMCL1CISD1SLC16A3
SCHEMBL8129600 0.81 AKR1C3 (0.70) KDM4EEGFRMCL1CISD1SLC16A3
SCHEMBL11442125 0.81 EGFR (0.69) KDM4EEGFRMCL1CISD1SLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9200410-B2 Electrophotographic recording sheet and recorded material YUPO CORPORATION (JP) 2015-12-01 US disclosed
EP-2149818-B1 ELECTROPHOTOGRAPH RECORDING SHEET AND RECORDED MATERIAL YUPO CORP (JP) 2014-06-04 EP disclosed
US-20100291363-A1 ELECTROPHOTOGRAPHIC RECORDING SHEET AND RECORDED MATERIAL YUPO CORPORATION (JP) 2010-11-18 US disclosed
EP-2149818-A1 ELECTROPHOTOGRAPH RECORDING SHEET AND RECORDED MATERIAL Yupo Corporation (JP) 2010-02-03 EP disclosed
EP-1275668-A1 PHOTOCURABLE COMPOSITION, CURED OBJECT, AND PROCESS FOR PRODUCING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2003-01-15 EP disclosed