Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 8/20 | 0.35 |
| ▸ | RARA | P10276 | 4/20 | 0.35 |
| ▸ | RARB | P10826 | 4/20 | 0.35 |
| ▸ | RARG | P13631 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13259641 | 0.86 | — | — | |
| SCHEMBL15395855 | 0.86 | — | — | |
| SCHEMBL13316574 | 0.86 | — | — | |
| SCHEMBL20349084 | 0.84 | ALDH1A1 (0.48) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL10069092 | 0.81 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL15395856 | 0.81 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL15396102 | 0.81 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL11858480 | 0.79 | ALDH1A1 (0.43) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL11858484 | 0.79 | ALDH1A1 (0.43) | ALDH1A1ALOX15RECQLHSD17B10TDP1 | |
| SCHEMBL456364 | 0.77 | ALDH1A1 (0.46) | ALDH1A1ALOX15RECQLHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017090007-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF UREA CYCLE DISORDERS AND HEPATIC DISEASES | RAO M SURYA (IN) | 2017-06-01 | — | — | WO | disclosed |
| WO-2016203352-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | MOHAN M ALAPATI (IN) | 2016-12-22 | — | — | WO | disclosed |