Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | GALK1 | P51570 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | PLEC | Q15149 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12908005 | 0.89 | HPSE (0.61) | HPSETDP1DUSP3PTPN5PTPN11 | |
| SCHEMBL19427482 | 0.86 | POLB (0.48) | HPSETDP1DUSP3PTPN5PTPN11 | |
| SCHEMBL11732302 | 0.81 | TDP1 (0.60) | HPSETDP1DUSP3PTPN5PTPN11 | |
| SCHEMBL15887767 | 0.81 | MAPK1 (0.48) | HPSETDP1DUSP3PTPN5PTPN11 | |
| SCHEMBL4449454 | 0.80 | CA2 (0.43) | HPSETDP1DUSP3PTPN5PTPN11 | |
| SCHEMBL15887279 | 0.80 | HPSE (0.43) | HPSETDP1DUSP3PTPN5PTPN11 | |
| SCHEMBL23481023 | 0.80 | CA2 (0.43) | HPSETDP1DUSP3PTPN5PTPN11 | |
| SCHEMBL21017071 | 0.79 | CA2 (0.38) | HPSETDP1DUSP3PTPN5PTPN11 | |
| SCHEMBL22293767 | 0.79 | NPC1 (0.58) | HPSETDP1DUSP3PTPN5PTPN11 | |
| SCHEMBL12171714 | 0.78 | HPSE (0.54) | HPSETDP1DUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160369055-A1 | A QUICK RESPONSIVE, SHAPE MEMORY THERMOSET POLYIMIDE AND PREPARATION METHOD THEREOF | HARBIN INSTITUTE OF TECHNOLOGY (CN) | 2016-12-22 | — | — | US | disclosed |