Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 9/20 | 0.38 |
| ▸ | SLC5A1 | P13866 | 8/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20373353 | 0.89 | HDAC1 (0.40) | L3MBTL1HTTHDAC1HDAC8HDAC6 | |
| SCHEMBL16905987 | 0.89 | L3MBTL1 (0.46) | L3MBTL1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL18326360 | 0.88 | HDAC6 (0.42) | L3MBTL1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL16905954 | 0.88 | HDAC1 (0.40) | CPT1ACPT1BL3MBTL1HDAC1HDAC8 | |
| SCHEMBL18326361 | 0.85 | SCN9A (0.39) | L3MBTL1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL16905841 | 0.85 | L3MBTL1 (0.53) | L3MBTL1USP2HTTKDM4ESLC5A2 | |
| SCHEMBL16896867 | 0.84 | BRD4 (0.41) | CPT1ACPT1BBRD4 | |
| SCHEMBL16905984 | 0.83 | BRD4 (0.54) | L3MBTL1TSHRALOX15KMOBRD4 | |
| SCHEMBL16906045 | 0.80 | L3MBTL1 (0.49) | L3MBTL1USP2KDM4ESLC5A2SLC5A1 | |
| SCHEMBL18326362 | 0.78 | L3MBTL1 (0.46) | L3MBTL1TSHRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10590118-B2 | Bicyclic heterocyclic derivatives as bromodomain inhibitors | ORION CORPORATION (FI) | 2020-03-17 | — | — | US | disclosed |
| US-20160368906-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORPORATION (FI) | 2016-12-22 | — | — | US | disclosed |
| US-20160368906-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORPORATION (FI) | 2016-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368906-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | BRD1, BRD2, BRD3 | CPT1A 1211/4885CPT1B 1150/4885L3MBTL1 2541/4885 |
| US-10590118-B2 | Bicyclic heterocyclic derivatives as bromodomain inhibitors | BRD1, BRD2, BRD3 | CPT1A 1211/4885CPT1B 1150/4885L3MBTL1 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.