SCHEMBL18327490

SCHEMBL18327490

c1ccc(-c2cccc(-c3nc(-c4cccc(-c5cncnc5)c4)nc(-c4cccc(-c5cncnc5)c4)n3)c2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.65
CYP2A6 P11509 1/20 0.45
GP6 Q9HCN6 1/20 0.44
KAT6A Q92794 1/20 0.43
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
MKNK1 Q9BUB5 1/20 0.42
MKNK2 Q9HBH9 1/20 0.42
NPC1 O15118 1/20 0.42
NFKB1 P19838 1/20 0.42
RAB9A P51151 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CYP19A1 P11511 1/20 0.42
KMO O15229 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18327441 0.96 ATM (0.61) ATMCYP2A6GP6KAT6ACYP11B1
SCHEMBL21982109 0.96 ATM (0.61) ATMCYP2A6GP6KAT6ACYP11B1
SCHEMBL18327335 0.96 ATM (0.59) ATMCYP2A6GP6KAT6ACYP11B1
SCHEMBL29512037 0.94 ATM (0.54) ATMCYP2A6GP6KAT6ACYP11B1
SCHEMBL21438413 0.94 ATM (0.54) ATMCYP2A6GP6KAT6ACYP11B1
SCHEMBL15298546 0.91 ATM (0.59) ATMCYP2A6GP6KAT6ASMN1; SMN2
SCHEMBL10071701 0.91 ATM (0.59) ATMCYP2A6GP6KAT6ASMN1; SMN2
SCHEMBL9957170 0.91 ATM (0.59) ATMCYP2A6GP6KAT6ASMN1; SMN2
SCHEMBL15298544 0.91 ATM (0.59) ATMCYP2A6GP6KAT6ASMN1; SMN2
SCHEMBL15298547 0.91 ATM (0.59) ATMCYP2A6GP6KAT6ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320120-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-05 US disclosed
US-20230320120-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-05 US disclosed
US-9812652-B2 Cyclic azine compound having adamantyl group, production method, and organic electroluminescent device containing it as constituent component TOSOH CORPORATION (JP) 2017-11-07 US disclosed
US-20160372678-A1 CYCLIC AZINE COMPOUND HAVING ADAMANTYL GROUP, PRODUCTION METHOD, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING IT AS CONSTITUENT COMPONENT TOSOH CORPORATION (JP) 2016-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160372678-A1 CYCLIC AZINE COMPOUND HAVING ADAMANTYL GROUP, PRODUCTION METHOD, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING IT AS CONSTITUENT COMPONENT CHRM1, AFF1, AZI2 ATM 2256/4885CYP2A6 1219/4885GP6 2485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.