SCHEMBL18328151

SCHEMBL18328151

COC(=O)[C@H](CCl)N(C)C(=O)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 2/20 0.54
CTSL P07711 1/20 0.46
CTSB P07858 1/20 0.46
CTSS P25774 1/20 0.46
CTSK P43235 1/20 0.46
ALDH1A1 P00352 4/20 0.45
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
EPOR P19235 1/20 0.41
CCR6 P51684 1/20 0.41
PAX8 Q06710 1/20 0.41
CTRB1 P17538 2/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
ALOX15 P16050 1/20 0.41
FOLH1 Q04609 1/20 0.41
PPARG P37231 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22165392 0.87 ABCB1 (0.55) ABCB1CTSLCTSBCTSSCTSK
SCHEMBL22165390 0.87 ABCB1 (0.55) ABCB1CTSLCTSBCTSSCTSK
SCHEMBL22457646 0.87 ABCB1 (0.62) ABCB1CTSLCTSBCTSSCTSK
SCHEMBL8615966 0.87 ABCB1 (0.55) ABCB1CTSLCTSBCTSSCTSK
SCHEMBL11302270 0.85 ABCB1 (0.53) ABCB1CTSLCTSBCTSSCTSK
SCHEMBL11306130 0.85 CTSK (0.58) ABCB1CTSLCTSBCTSSCTSK
SCHEMBL11306127 0.85 CTSK (0.58) ABCB1CTSLCTSBCTSSCTSK
SCHEMBL9386683 0.83 ABCB1 (0.51) ABCB1CTSLCTSBCTSSCTSK
SCHEMBL18379807 0.83 ABCB1 (0.51) ABCB1CTSLCTSBCTSSCTSK
SCHEMBL10788987 0.82 ABCB1 (0.59) ABCB1CTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016202894-A1 METHOD OF CONVERTING ALCOHOL TO HALIDE UNIVERSITAET DES SAARLANDES (DE) 2016-12-22 WO disclosed