Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.40 |
| ▸ | NPY1R | P25929 | 9/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.40 |
| ▸ | NPY2R | P49146 | 5/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18328775 | 1.00 | NPY4R (0.40) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| SCHEMBL20864155 | 0.93 | SIRT5 (0.44) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| SCHEMBL10029497 | 0.93 | SIRT5 (0.44) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| Leupeptin SCHEMBL13933715 | 0.91 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| Leupeptin SCHEMBL583830 | 0.91 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| Leupeptin SCHEMBL4669504 | 0.91 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| Leupeptin SCHEMBL11021602 | 0.91 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| Leupeptin SCHEMBL11596919 | 0.90 | NPY4R (0.46) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL3308386 | 0.89 | NPY4R (0.45) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL30643187 | 0.89 | NPY4R (0.45) | NPY4RNPY1RNPY5RNPY2RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016204197-A1 | PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF | 学校法人東京理科大学 | 2016-12-22 | — | — | WO | disclosed |