SCHEMBL18328876

SCHEMBL18328876

C=CC(=O)OCCCCCCOc1ccc(C(=O)Oc2ccc(CCCCCC)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 6/20 0.64
NPC1 O15118 3/20 0.56
LMNA P02545 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
NFKB1 P19838 3/20 0.56
NFKB2 Q00653 3/20 0.56
RELA Q04206 3/20 0.56
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
THRA P10827 4/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
MAPT P10636 4/20 0.49
HPGD P15428 2/20 0.49
ALDH1A1 P00352 1/20 0.49
POLB P06746 1/20 0.49
PRSS1 P07477 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13927207 1.00 THRB (0.64) THRBNPC1LMNASMN1; SMN2NFKB1
SCHEMBL9996685 1.00 THRB (0.64) THRBNPC1LMNASMN1; SMN2NFKB1
SCHEMBL16885029 1.00 THRB (0.64) THRBNPC1LMNASMN1; SMN2NFKB1
SCHEMBL15855561 1.00 THRB (0.64) THRBNPC1LMNASMN1; SMN2NFKB1
SCHEMBL15855658 1.00 THRB (0.64) THRBNPC1LMNASMN1; SMN2NFKB1
SCHEMBL15855554 1.00 THRB (0.64) THRBNPC1LMNASMN1; SMN2NFKB1
SCHEMBL15855532 1.00 THRB (0.64) THRBNPC1LMNASMN1; SMN2NFKB1
SCHEMBL14085075 1.00 THRB (0.64) THRBNPC1LMNASMN1; SMN2NFKB1
SCHEMBL15855662 1.00 THRB (0.64) THRBNPC1LMNASMN1; SMN2NFKB1
SCHEMBL29343548 1.00 THRB (0.64) THRBNPC1LMNASMN1; SMN2NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed
EP-3112930-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC Corporation (JP) 2017-01-04 EP disclosed
US-20160370626-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-12-22 US disclosed
US-20160370626-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-12-22 US disclosed