Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.46 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19355275 | 0.84 | TAAR1 (1.00) | TAAR1ATMMEN1KMT2AL3MBTL1 | |
| SCHEMBL1878 | 0.84 | TAAR1 (1.00) | TAAR1ATMMEN1KMT2AL3MBTL1 | |
| Nitric Acid SCHEMBL18329335 | 0.84 | TMEM97 (0.75) | TAAR1ATMSIGMAR1TMEM97SMN1; SMN2 | |
| SCHEMBL7236339 | 0.82 | TAAR1 (0.95) | TAAR1ATMMEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1696934 | 0.82 | TAAR1 (0.95) | TAAR1ATMMEN1KMT2AL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL19693169 | 0.82 | TAAR1 (0.95) | TAAR1ATMMEN1KMT2AL3MBTL1 | |
| SCHEMBL27896457 | 0.82 | TAAR1 (0.95) | TAAR1ATMMEN1KMT2AL3MBTL1 | |
| Nitrous Acid SCHEMBL18329333 | 0.81 | TAAR1 (0.76) | TAAR1ATMMEN1KMT2AL3MBTL1 | |
| Sulfuric Acid SCHEMBL1829177 | 0.81 | TAAR1 (0.76) | TAAR1ATMMEN1KMT2AL3MBTL1 | |
| Formic Acid SCHEMBL3537931 | 0.81 | TAAR1 (0.76) | TAAR1ATMMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9526793-B1 | Salts of phenylethylamines and inorganic acids and methods of use thereof | KRAMER RONALD (US) | 2016-12-27 | — | — | US | disclosed |