SCHEMBL1832992

SCHEMBL1832992

O=C(O)CCCCCNN1C(=O)C=CC1=O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 4/20 0.61
PTGS2 P35354 4/20 0.61
MAPK1 P28482 1/20 0.46
PRMT1 Q99873 1/20 0.46
CYP4Z1 Q86W10 4/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C8 P10632 1/20 0.44
CYP2B6 P20813 1/20 0.44
CYP4F8 P98187 1/20 0.44
CYP4F12 Q9HCS2 1/20 0.44
LMNA P02545 1/20 0.43
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43
PMP22 Q01453 1/20 0.43
ADRA1A P35348 1/20 0.43
F13A1 P00488 3/20 0.42
ALDH1A1 P00352 2/20 0.41
TBXA2R P21731 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29280307 0.93 PTGS1 (0.55) PTGS1PTGS2MAPK1CYP4Z1CYP1A2
SCHEMBL1147642 0.85 PTGS1 (0.48) PTGS1PTGS2MAPK1LMNAALDH1A1
SCHEMBL10800016 0.84 MGLL (0.48) PTGS1PTGS2MAPK1LMNAPMP22
SCHEMBL27315404 0.84 PTGS1 (0.42) PTGS1PTGS2MAPK1CYP4Z1CYP1A2
SCHEMBL15579098 0.78 PTGS1 (0.81) PTGS1PTGS2MAPK1PRMT1LMNA
SCHEMBL3441080 0.77 CDC25A (0.51) MAPK1CYP4Z1CYP1A2CYP2C8CYP2B6
SCHEMBL24939859 0.76 PTGS1 (1.00) PTGS1PTGS2MAPK1LMNATSHR
SCHEMBL8779453 0.76 PTGS1 (1.00) PTGS1PTGS2MAPK1LMNATSHR
SCHEMBL3291535 0.76 PTGS1 (1.00) PTGS1PTGS2MAPK1LMNATSHR
SCHEMBL6934781 0.76 PTGS1 (1.00) PTGS1PTGS2MAPK1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1534324-B1 TUMOR SPECIFIC OLIGOSACCHARIDE EPITOPES AND USE THEREOF GLYKOS FINLAND OY (FI) 2019-01-16 EP disclosed
US-20180055928-A1 Tumor specific oligosaccharide epitopes and use thereof GLYKOS FINLAND OY (FI) 2018-03-01 US disclosed
US-20140234318-A1 TUMOR SPECIFIC OLIGOSACCHARIDE EPITOPES AND USE THEREOF GLYKOS FINLAND OY (FI) 2014-08-21 US disclosed
US-8697061-B2 Tumor specific oligosaccharide epitopes and use thereof GLYKOS FINLAND OY (FI) 2014-04-15 US disclosed
EP-2322209-A2 Tumor specific oligosaccharide epitopes and use thereof Glykos Finland Oy (FI) 2011-05-18 EP disclosed
US-20060014672-A1 Tumor specific oligosaccharide epitopes and use thereof GLYKOS FINLAND OY (FI) 2006-01-19 US disclosed
EP-0487610-B1 PROHORMONE CLEAVAGE SITE BLOCKING ANTIBODY CHIRON CORP (US) 2000-02-09 EP disclosed
US-6020206-A Homocysteine assay NEXSTAR PHARMACEUTICALS, INC. (US) 2000-02-01 US disclosed
EP-0491828-B1 PEPTIDES FROM GTPase-ACTIVATING PROTEIN (GAP), DIAGNOSTIC AND THERAPEUTIC USE THEREOF CHIRON CORP (US) 1999-06-16 EP disclosed
WO-1998059242-A1 HOMOCYSTEINE ASSAY NEXSTAR PHARMACEUTICALS, INC. (US) 1998-12-30 WO disclosed
US-4894226-A SPACERS, CROSSLINKING CETUS CORPORATION (US) 1990-01-16 US disclosed
WO-1989011547-A1 METHOD FOR HLA DP TYPING CETUS CORPORATION (US) 1989-11-30 WO disclosed
WO-1989011548-A1 IMMOBILIZED SEQUENCE-SPECIFIC PROBES CETUS CORPORATION (US) 1989-11-30 WO disclosed
CN-1037349-A Novel multipolymer and with this copolymer-modified hemocuprein KURARAY CO (JP) 1989-11-22 CN disclosed
WO-1989002932-A1 A COVALENT OLIGONUCLEOTIDE-HORSERADISH PEROXIDASE CONJUGATE CETUS CORPORATION (US) 1989-04-06 WO disclosed
WO-1989002931-A1 OLIGONUCLEOTIDE FUNCTIONALIZING REAGENTS AND METHODS CETUS CORPORATION (US) 1989-04-06 WO disclosed
US-4798787-A POLYCLONAL CETUS CORPORATION (US) 1989-01-17 US disclosed
US-4762706-A ANTICANCER CETUS CORPORATION (US) 1988-08-09 US disclosed
EP-0177814-A2 Peptide antibodies and their use in detecting oncogene products CETUS CORPORATION (US) 1986-04-16 EP disclosed
EP-0175360-A2 Peptide antibodies and their use in detecting oncogene products CETUS CORPORATION (US) 1986-03-26 EP disclosed