Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1835123 | 0.90 | TAAR1 (0.42) | TAAR1PPARD | |
| SCHEMBL17754402 | 0.84 | PPARD (0.44) | TAAR1PPARDALDH1A1KDM4ETSHR | |
| SCHEMBL282093 | 0.82 | PPARD (0.47) | TAAR1PPARDALDH1A1KDM4ETSHR | |
| SCHEMBL10912425 | 0.82 | TAAR1 (0.44) | TAAR1PPARDALDH1A1KDM4ETSHR | |
| SCHEMBL7393069 | 0.82 | GFER (0.45) | PPARDTSHRTDP1LMNA | |
| SCHEMBL5248630 | 0.81 | CETP (0.47) | PPARDTSHRPOLB | |
| SCHEMBL1489170 | 0.81 | NPY5R (0.45) | ALDH1A1KDM4ETSHRHPGDTDP1 | |
| SCHEMBL2955651 | 0.79 | PPARD (0.42) | PPARDALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL6898444 | 0.79 | PPARD (0.42) | PPARDTSHR | |
| SCHEMBL978688 | 0.78 | PPARD (0.39) | PPARDALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321287-A1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010010014-A1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-01-28 | — | — | WO | disclosed |