Phthalic Acid

Phthalic Acid

SCHEMBL1833083

CNCCO.CNCCO.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
ALOX15 P16050 1/20 0.56
AKR1C3 P42330 2/20 0.50
HTT P42858 2/20 0.47
KDM4E B2RXH2 3/20 0.46
KMT2A Q03164 2/20 0.46
GLA P06280 1/20 0.46
APEX1 P27695 1/20 0.46
HSD17B10 Q99714 2/20 0.44
HPGD P15428 2/20 0.44
CDC25B P30305 2/20 0.44
CDC25A P30304 1/20 0.44
ATM Q13315 1/20 0.44
CA12 O43570 2/20 0.44
CA9 Q16790 2/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
HMGB1 P09429 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylic Acid SCHEMBL1835282 0.89 ALDH1A1 (0.62) ALDH1A1ALOX15HTTKDM4EKMT2A
SCHEMBL1836779 0.88 ALDH1A1 (0.63) ALDH1A1AKR1C3KMT2AHPGDSMN1; SMN2
SCHEMBL1833003 0.88 GAA (0.51) ALDH1A1ALOX15SMN1; SMN2
SCHEMBL1831602 0.87 AKR1C3 (0.41) ALDH1A1ALOX15AKR1C3HTTKDM4E
Benzoic Acid SCHEMBL1834001 0.84 TSHR (0.56) ALDH1A1ALOX15KDM4EKMT2AHPGD
Phthalic Acid SCHEMBL21195154 0.83 ALDH1A1 (0.61) ALDH1A1ALOX15AKR1C3HTTKDM4E
Phthalic Acid SCHEMBL1833827 0.83 ALDH1A1 (0.61) ALDH1A1ALOX15AKR1C3HTTKDM4E
SCHEMBL1835458 0.82 CYP1A2 (0.38) ALDH1A1ALOX15AKR1C3HTTKDM4E
Phthalic Acid SCHEMBL5875168 0.80 ALDH1A1 (0.78) ALDH1A1ALOX15AKR1C3KDM4EHSD17B10
Phthalic Acid SCHEMBL3671128 0.80 ALDH1A1 (0.78) ALDH1A1ALOX15AKR1C3HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US claimed
US-9328220-B2 Liquids INNOVIA FILMS LIMITED (GB) 2016-05-03 US disclosed
US-8992798-B2 Liquids INNOVIA FILMS LIMITED (GB) 2015-03-31 US disclosed
US-8784686-B2 Liquids INNOVIA FILMS LIMITED (GB) 2014-07-22 US disclosed
US-20140187684-A1 LIQUIDS INNOVIA FILMS LIMITED (GB) 2014-07-03 US disclosed
US-20110257433-A1 LIQUIDS THE UNIVERSITY OF YORK (GB) 2011-10-20 US disclosed
EP-2322497-A1 Ionic liquids comprising nitrogen containing cations Innovia Films Limited (GB) 2011-05-18 EP disclosed
US-20080221361-A1 Ionic Liquids BIONIQS LIMITED (GB) 2008-09-11 US disclosed
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US disclosed