Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10003334 | 0.91 | ALOX5 (0.39) | ALOX5NOD1NOD2NPSR1HPGD | |
| SCHEMBL10003329 | 0.91 | ALOX5 (0.39) | ALOX5NOD1NOD2NPSR1HPGD | |
| SCHEMBL18331988 | 0.91 | ALOX5 (0.41) | ALOX5NOD1NOD2NPSR1HPGD | |
| SCHEMBL18331911 | 0.89 | ALOX5 (0.38) | ALOX5NOD1NOD2NPSR1HPGD | |
| SCHEMBL10003580 | 0.89 | ALOX5 (0.39) | ALOX5NOD1NOD2NPSR1HPGD | |
| SCHEMBL10003582 | 0.89 | ALOX5 (0.39) | ALOX5NOD1NOD2NPSR1HPGD | |
| SCHEMBL10002978 | 0.88 | ALOX5 (0.38) | ALOX5NOD1NOD2NPSR1HPGD | |
| SCHEMBL10002979 | 0.88 | ALOX5 (0.38) | ALOX5NOD1NOD2NPSR1HPGD | |
| SCHEMBL10003003 | 0.88 | ALOX5 (0.43) | ALOX5NOD1NOD2NPSR1HPGD | |
| SCHEMBL10003655 | 0.88 | ALOX5 (0.43) | ALOX5NOD1NOD2NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016204261-A1 | AMINOPYRAZOLE DERIVATIVES | 中外製薬株式会社 | 2016-12-22 | — | — | WO | disclosed |