Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18332208 | 0.86 | LMNA (0.37) | SRD5A1SRD5A2 | |
| SCHEMBL18331842 | 0.82 | SRD5A1 (0.30) | SRD5A1SRD5A2 | |
| SCHEMBL20084181 | 0.82 | SRD5A1 (0.36) | SRD5A1SRD5A2SYKXDH | |
| SCHEMBL18331896 | 0.82 | GRIN2D (0.42) | SRD5A1SRD5A2 | |
| SCHEMBL20085099 | 0.81 | SRD5A1 (0.32) | SRD5A1SRD5A2SYKXDH | |
| SCHEMBL18332159 | 0.79 | HRH3 (0.39) | — | |
| SCHEMBL20085009 | 0.78 | SRD5A1 (0.32) | SRD5A1SRD5A2SYKXDH | |
| SCHEMBL21970583 | 0.78 | SRD5A1 (0.36) | SRD5A1SRD5A2SYKXDH | |
| SCHEMBL18332146 | 0.78 | KDM4E (0.52) | XDH | |
| SCHEMBL20084826 | 0.78 | SYK (0.34) | SRD5A1SRD5A2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312172-B1 | AMINOPYRAZOLE DERIVATIVES USEFUL AS SRC KINASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2020-05-06 | — | — | EP | disclosed |
| EP-3312172-B1 | AMINOPYRAZOLE DERIVATIVES USEFUL AS SRC KINASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2020-05-06 | — | — | EP | disclosed |
| US-10479780-B2 | Aminopyrazole derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2019-11-19 | — | — | US | disclosed |
| US-20180362509-A1 | AMINOPYRAZOLE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2018-12-20 | — | — | US | disclosed |
| EP-3312172-A1 | AMINOPYRAZOLE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-04-25 | — | — | EP | disclosed |
| EP-3312172-A1 | AMINOPYRAZOLE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-04-25 | — | — | EP | disclosed |
| WO-2016204261-A1 | AMINOPYRAZOLE DERIVATIVES | 中外製薬株式会社 | 2016-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10479780-B2 | Aminopyrazole derivatives | SRC, GRK2, GRK3 | SRD5A1 1012/4885SRD5A2 1268/4885ACACB 2135/4885 |
| US-20180362509-A1 | AMINOPYRAZOLE DERIVATIVES | SRC, GRK2, GRK3 | SRD5A1 1012/4885SRD5A2 1268/4885ACACB 2135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.