Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654936 | 0.83 | PLAU (0.35) | PLAUCYP3A4CYP2C19GAAALDH1A1 | |
| SCHEMBL21994706 | 0.80 | PLAU (0.40) | PLAUALDH1A1MAPT | |
| SCHEMBL15674757 | 0.80 | PLAU (0.42) | PLAUALDH1A1MAPT | |
| SCHEMBL18335140 | 0.79 | PLAU (0.37) | PLAUALDH1A1MAPT | |
| SCHEMBL16654525 | 0.77 | PLAU (0.40) | PLAUALDH1A1MAPT | |
| SCHEMBL29268175 | 0.77 | PLAU (0.40) | PLAUALDH1A1MAPT | |
| SCHEMBL29989503 | 0.77 | PLAU (0.40) | PLAUALDH1A1MAPT | |
| SCHEMBL25195217 | 0.72 | PLAU (0.37) | PLAUALDH1A1MAPTL3MBTL1 | |
| SCHEMBL16540711 | 0.72 | PLAU (0.40) | PLAU | |
| SCHEMBL16552187 | 0.72 | PLAU (0.40) | PLAUGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10029986-B2 | Alkynyl pyridine-substituted amide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
| US-20170008847-A1 | ALKYNYL PYRIDINE-SUBSTITUTED AMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-01-12 | — | — | US | disclosed |
| EP-3109234-A1 | ALKYNYLPYRIDINE-SUBSTITUTED AMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2016-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10029986-B2 | Alkynyl pyridine-substituted amide compound and pesticide | CHRM1, CHRM2, CHRM3 | PLAU 4881/4885CYP3A4 173/4885CYP2C19 117/4885 |
| US-20170008847-A1 | ALKYNYL PYRIDINE-SUBSTITUTED AMIDE COMPOUND AND PESTICIDE | CHRM1, CHRM2, CHRM3 | PLAU 4881/4885CYP3A4 173/4885CYP2C19 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.