Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18335085 | 0.87 | CHRNB2 (0.38) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18335126 | 0.80 | MAPT (0.32) | — | |
| SCHEMBL18335152 | 0.75 | EGLN1 (0.39) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18335115 | 0.74 | CHRNB2 (0.39) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18335098 | 0.74 | EGLN1 (0.44) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL14920915 | 0.72 | GRIN2B (0.40) | GRIN2B | |
| SCHEMBL18335112 | 0.71 | CHRNB2 (0.39) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18335097 | 0.71 | CHRNB2 (0.37) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18335073 | 0.71 | EGLN1 (0.44) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL18335095 | 0.70 | EGLN1 (0.39) | CHRNB2CHRNA2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10029986-B2 | Alkynyl pyridine-substituted amide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-07-24 | — | — | US | disclosed |
| US-20170008847-A1 | ALKYNYL PYRIDINE-SUBSTITUTED AMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-01-12 | — | — | US | disclosed |
| EP-3109234-A1 | ALKYNYLPYRIDINE-SUBSTITUTED AMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2016-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10029986-B2 | Alkynyl pyridine-substituted amide compound and pesticide | CHRM1, CHRM2, CHRM3 | CHRNB2 800/4885CHRNA2 279/4885CHRNB4 576/4885 |
| US-20170008847-A1 | ALKYNYL PYRIDINE-SUBSTITUTED AMIDE COMPOUND AND PESTICIDE | CHRM1, CHRM2, CHRM3 | CHRNB2 800/4885CHRNA2 279/4885CHRNB4 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.