Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | SELL | P14151 | 1/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL9725105 | 0.88 | CYP1A2 (0.50) | CYP1A2HMGB1ALDH1A1ALOX15KDM4E | |
| Monoethanolamine SCHEMBL1834713 | 0.87 | HMGB1 (0.50) | HMGB1ALDH1A1ALOX15KDM4ETSHR | |
| SCHEMBL22989 | 0.83 | CYP1A2 (0.61) | CYP1A2HMGB1ALDH1A1ALOX15KDM4E | |
| SCHEMBL29445717 | 0.83 | CYP1A2 (0.61) | CYP1A2HMGB1ALDH1A1ALOX15KDM4E | |
| SCHEMBL1988762 | 0.83 | CYP1A2 (0.61) | CYP1A2HMGB1ALDH1A1ALOX15KDM4E | |
| SCHEMBL5550251 | 0.80 | CYP1A2 (0.58) | CYP1A2HMGB1ALDH1A1ALOX15KDM4E | |
| Hydrochloric Acid SCHEMBL18124413 | 0.80 | CYP1A2 (0.58) | CYP1A2HMGB1ALDH1A1ALOX15KDM4E | |
| Hydrochloric Acid SCHEMBL10351177 | 0.80 | CYP1A2 (0.58) | CYP1A2HMGB1ALDH1A1ALOX15KDM4E | |
| Mellitic Acid SCHEMBL2426221 | 0.80 | CYP1A2 (0.58) | CYP1A2HMGB1ALDH1A1ALOX15KDM4E | |
| Ammonia Solution, Strong SCHEMBL5023112 | 0.80 | CYP1A2 (0.58) | CYP1A2HMGB1ALDH1A1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328220-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2016-05-03 | — | — | US | disclosed |
| US-8992798-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2015-03-31 | — | — | US | disclosed |
| US-8784686-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2014-07-22 | — | — | US | disclosed |
| US-20140187684-A1 | LIQUIDS | INNOVIA FILMS LIMITED (GB) | 2014-07-03 | — | — | US | disclosed |
| US-20110257433-A1 | LIQUIDS | THE UNIVERSITY OF YORK (GB) | 2011-10-20 | — | — | US | disclosed |
| EP-2322497-A1 | Ionic liquids comprising nitrogen containing cations | Innovia Films Limited (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | disclosed |