Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL9725011 | 0.89 | ALDH1A1 (0.52) | HMGB1ALDH1A1ALOX15ALBG6PD | |
| Monoethanolamine SCHEMBL1833522 | 0.87 | CYP1A2 (0.44) | HMGB1ALDH1A1ALOX15CASP6AKR1C3 | |
| Phthalic Acid SCHEMBL1833350 | 0.85 | ALDH1A1 (0.67) | HMGB1ALDH1A1ALOX15AKR1C3KDM4E | |
| Phthalic Acid SCHEMBL6931442 | 0.85 | ALDH1A1 (0.67) | HMGB1ALDH1A1ALOX15AKR1C3KDM4E | |
| SCHEMBL23288 | 0.84 | ALDH1A1 (0.63) | HMGB1ALDH1A1ALOX15ALBG6PD | |
| SCHEMBL711798 | 0.84 | ALDH1A1 (0.63) | HMGB1ALDH1A1ALOX15ALBG6PD | |
| Alcohol SCHEMBL28252328 | 0.83 | ALDH1A1 (0.50) | HMGB1ALDH1A1ALOX15AKR1C3KDM4E | |
| SCHEMBL723062 | 0.82 | ALDH1A1 (0.60) | HMGB1ALDH1A1ALOX15ALBG6PD | |
| SCHEMBL1535448 | 0.82 | ALDH1A1 (0.60) | HMGB1ALDH1A1ALOX15ALBG6PD | |
| Hydrochloric Acid SCHEMBL1564027 | 0.82 | ALDH1A1 (0.60) | HMGB1ALDH1A1ALOX15ALBG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328220-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2016-05-03 | — | — | US | disclosed |
| US-8992798-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2015-03-31 | — | — | US | disclosed |
| US-8784686-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2014-07-22 | — | — | US | disclosed |
| US-20140187684-A1 | LIQUIDS | INNOVIA FILMS LIMITED (GB) | 2014-07-03 | — | — | US | disclosed |
| US-20110257433-A1 | LIQUIDS | THE UNIVERSITY OF YORK (GB) | 2011-10-20 | — | — | US | disclosed |
| EP-2322497-A1 | Ionic liquids comprising nitrogen containing cations | Innovia Films Limited (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | disclosed |