Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830963 | 0.84 | ADORA2A (0.65) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL241802 | 0.84 | ADORA2A (0.65) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL2883240 | 0.84 | ADORA2A (0.60) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL241132 | 0.84 | ADORA2A (0.60) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL240011 | 0.83 | ADORA2A (0.57) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL293054 | 0.83 | ADORA2A (0.55) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL1843512 | 0.82 | ADORA2A (0.55) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL238863 | 0.82 | ADORA2A (0.55) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL293561 | 0.81 | ADORA2A (0.55) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL241166 | 0.81 | ADORA2A (0.55) | ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322525-A1 | Purine derivatives for use as adenosin A2A receptor agonists | Novartis AG (CH) | 2011-05-18 | — | — | EP | disclosed |