SCHEMBL1833944 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	CYP1A2	P05177	2/20	0.38

▸	CYP2D6	P10635	2/20	0.38

▸	GSK3B	P49841	9/20	0.37

▸	ALDH1A1	P00352	4/20	0.35

▸	MAPT	P10636	2/20	0.35

▸	THRB	P10828	1/20	0.35

▸	MGLL	Q99685	1/20	0.35

▸	CYP3A4	P08684	1/20	0.34

▸	PSD	A5PKW4	1/20	0.34

▸	FAAH	O00519	1/20	0.34

▸	POLB	P06746	1/20	0.34

▸	KDM4E	B2RXH2	2/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	TDP1	Q9NUW8	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1836064	0.80	GSK3B (0.45)	CYP2D6GSK3B
SCHEMBL1834667	0.74	GSK3B (0.51)	CYP1A2CYP2D6GSK3B
SCHEMBL1832336	0.73	GSK3B (0.47)	CYP2D6GSK3B
SCHEMBL2065123	0.73	GSK3B (0.47)	CYP2D6GSK3B
SCHEMBL1834981	0.72	GSK3B (0.46)	CYP2D6GSK3BCYP3A4
SCHEMBL1833143	0.72	GSK3B (0.46)	CYP2D6GSK3BCYP3A4
SCHEMBL1830440	0.72	GSK3B (0.47)	CYP2D6GSK3B
SCHEMBL2064445	0.71	GSK3B (0.41)	CYP1A2CYP2D6GSK3BCYP3A4
SCHEMBL2065354	0.71	GSK3B (0.41)	CYP1A2CYP2D6GSK3BCYP3A4
SCHEMBL1833092	0.70	GSK3B (0.47)	CYP2D6GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2321316-A1	SUBSTITUTED PYRIMIDIN-4-ONE DERIVATIVES	Mitsubishi Tanabe Pharma Corporation (JP)	2011-05-18	—	—	EP	disclosed
WO-2009156865-A1	SUBSTITUTED PYRIMIDIN-4-ONE DERIVATIVES	MITSUBISHI TANABE PHARMA CORPORATION (JP)	2009-12-30	—	—	WO	disclosed