Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.45 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891480 | 0.97 | GSK3B (0.46) | GSK3BCAMKK2CYP2D6 | |
| SCHEMBL4380719 | 0.90 | GSK3B (0.44) | GSK3BCAMKK2CYP2D6 | |
| SCHEMBL1834667 | 0.84 | GSK3B (0.51) | GSK3BCYP2D6 | |
| SCHEMBL2065123 | 0.83 | GSK3B (0.47) | GSK3BCYP2D6 | |
| SCHEMBL1832336 | 0.83 | GSK3B (0.47) | GSK3BCYP2D6 | |
| SCHEMBL1833143 | 0.82 | GSK3B (0.46) | GSK3BCYP2D6 | |
| SCHEMBL1834981 | 0.82 | GSK3B (0.46) | GSK3BCYP2D6 | |
| SCHEMBL1830440 | 0.81 | GSK3B (0.47) | GSK3BCYP2D6 | |
| SCHEMBL1833944 | 0.80 | CYP1A2 (0.38) | GSK3BCYP2D6 | |
| SCHEMBL1833092 | 0.80 | GSK3B (0.47) | GSK3BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321316-A1 | SUBSTITUTED PYRIMIDIN-4-ONE DERIVATIVES | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-05-18 | — | — | EP | disclosed |
| WO-2009156865-A1 | SUBSTITUTED PYRIMIDIN-4-ONE DERIVATIVES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-12-30 | — | — | WO | disclosed |