Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1832210 | 0.91 | ZDHHC20 (0.53) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL1832212 | 0.91 | ZDHHC20 (0.53) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL11460809 | 0.87 | CA12 (0.44) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL6636617 | 0.87 | CA12 (0.44) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL19472462 | 0.85 | ZDHHC20 (0.45) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL1395669 | 0.84 | CA12 (0.54) | CA12CA9CA2APPALDH1A1 | |
| SCHEMBL11681109 | 0.84 | CA12 (0.54) | CA12CA9CA2APPALDH1A1 | |
| SCHEMBL1395625 | 0.84 | CA12 (0.54) | CA12CA9CA2APPALDH1A1 | |
| SCHEMBL19917777 | 0.82 | ZDHHC20 (0.50) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL19854404 | 0.82 | ZDHHC20 (0.50) | CA12CA9CA2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833870-B1 | DURABLE COATING COMPOSITIONS CONTAINING NOVEL ASPARTIC AMINE COMPOUNDS | DU PONT (US) | 2011-05-11 | — | — | EP | disclosed |
| US-7682665-B2 | Durable coating compositions containing novel aspartic amine compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-03-23 | — | — | US | disclosed |
| US-7674499-B2 | Durable coating compositions containing novel aspartic amine compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-03-09 | — | — | US | disclosed |
| EP-1833870-A1 | DURABLE COATING COMPOSITIONS CONTAINING NOVEL ASPARTIC AMINE COMPOUNDS | E.I.Du pont de nemours and company (US) | 2007-09-19 | — | — | EP | disclosed |
| US-7214828-B2 | Durable coating compositions containing novel aspartic amine compounds | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-05-08 | — | — | US | disclosed |
| US-20060155054-A1 | Durable coating compositions containing novel aspartic amine compounds | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-07-13 | — | — | US | disclosed |
| US-20060155148-A1 | Durable coating compositions containing novel aspartic amine compounds | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-07-13 | — | — | US | disclosed |
| US-20060155053-A1 | Durable coating compositions containing novel aspartic amine compounds | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-07-13 | — | — | US | disclosed |
| WO-2006066026-A1 | DURABLE COATING COMPOSITIONS CONTAINING NOVEL ASPARTIC AMINE COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060155148-A1 | Durable coating compositions containing novel aspartic amine compounds | H1-0, H1-2, H1-5 | CA12 388/4885CA9 1176/4885CA2 1378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.