Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161785 | 0.94 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL1834610 | 0.91 | ADORA3 (0.35) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL1832384 | 0.89 | ADORA3 (0.38) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL2161337 | 0.86 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL1833131 | 0.86 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL1835192 | 0.83 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL1836406 | 0.83 | ADORA3 (0.39) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL12402756 | 0.81 | HTT (0.33) | MEN1KMT2A | |
| SCHEMBL1833654 | 0.81 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BADORA1SKP2 | |
| SCHEMBL1838818 | 0.81 | ADORA3 (0.36) | ADORA3ADORA2AADORA2BADORA1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| EP-2318374-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010012442-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | DDT, BRD9, BCL2A1 | ADORA3 2498/4885ADORA2A 3815/4885ADORA2B 2286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.