Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5646973 | 0.86 | FFAR1 (0.53) | FFAR1PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL12707808 | 0.82 | FFAR1 (0.57) | FFAR1PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL1584822 | 0.80 | FFAR1 (0.77) | FFAR1PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL21135465 | 0.78 | HPGD (0.49) | FFAR1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL1585108 | 0.77 | FFAR1 (0.58) | FFAR1PPARGMEN1RAB9AKMT2A | |
| SCHEMBL180951 | 0.76 | GPR119 (0.48) | ALDH1A1SMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL1584862 | 0.74 | FFAR1 (0.58) | FFAR1PPARG | |
| SCHEMBL18787387 | 0.73 | HPGD (0.50) | FFAR1ALDH1A1SMN1; SMN2MEN1RAB9A | |
| SCHEMBL1584574 | 0.73 | FFAR1 (0.52) | FFAR1PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL29873861 | 0.73 | FFAR1 (0.55) | FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402318-A1 | DGAT inhibitors | Novartis AG (CH) | 2012-01-04 | — | — | EP | disclosed |