Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24926609 | 0.83 | SMN1; SMN2 (0.51) | ALDH1A1KDM4EHTTSMN1; SMN2CES2 | |
| SCHEMBL29868532 | 0.83 | TLR7 (0.52) | ALDH1A1KDM4EHTTSMN1; SMN2CES2 | |
| SCHEMBL13218343 | 0.83 | KDM4E (0.56) | ALDH1A1KDM4EHTTSMN1; SMN2CES2 | |
| SCHEMBL28790169 | 0.82 | NSUN3 (0.49) | ALDH1A1KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL8173813 | 0.82 | KDM4E (0.59) | ALDH1A1KDM4EHTTSMN1; SMN2CES2 | |
| SCHEMBL29835997 | 0.82 | MEN1 (0.50) | ALDH1A1KDM4EHTTSMN1; SMN2CES2 | |
| SCHEMBL21198407 | 0.82 | ANO1 (0.56) | ALDH1A1KDM4EHTTSMN1; SMN2CES2 | |
| SCHEMBL18918939 | 0.82 | MEN1 (0.50) | ALDH1A1KDM4EHTTSMN1; SMN2CES2 | |
| SCHEMBL20024124 | 0.82 | POLB (0.59) | ALDH1A1KDM4EHTTSMN1; SMN2CES2 | |
| SCHEMBL1570558 | 0.81 | TLR7 (0.58) | ALDH1A1KDM4EHTTSMN1; SMN2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743406-B9 | TMEM16A MODULATORS | TMEM16A LTD (GB) | 2023-03-08 | — | — | EP | claimed |
| EP-3743406-B1 | TMEM16A MODULATORS | TMEM16A LTD (GB) | 2022-12-28 | — | — | EP | claimed |
| CN-103102343-A | Preparation method of rupatadine fumarate | ANHUI YOUCARE KAIYUE PHARMACEUTICAL CO LTD | 2013-05-15 | — | — | CN | claimed |
| EP-0389189-B1 | Diazepine antiallergy agents | PFIZER LTD (GB) | 1994-05-18 | — | — | EP | claimed |
| US-5008263-A | Platelet activating factor antagonists; antiallergens; antiinflammatory agents | PFIZER INC. (US) | 1991-04-16 | — | — | US | claimed |
| EP-0389189-A2 | Diazepine antiallergy agents | Pfizer Limited (GB) | 1990-09-26 | — | — | EP | claimed |
| US-4715888-A | SYNERGISTIC MIXTURES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-29 | — | — | US | claimed |
| US-4496736-A | ALKALINE HYDROLYSIS OF ALKYLACRBOXYLIC AMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-29 | — | — | US | claimed |
| CN-114616226-B | Pyridine derivatives as TMEM16A modulators for the treatment of respiratory disorders | TMEM16A有限公司 | 2025-03-04 | — | — | CN | disclosed |
| US-20230278958-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2023-09-07 | — | — | US | disclosed |
| US-20230278958-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2023-09-07 | — | — | US | disclosed |
| US-20230226062-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2023-07-20 | — | — | US | disclosed |
| US-20230174538-A1 | Tricyclic heterocycles | MERCK PATENT GMBH (DE) | 2023-06-08 | — | — | US | disclosed |
| US-20230174538-A1 | Tricyclic heterocycles | MERCK PATENT GMBH (DE) | 2023-06-08 | — | — | US | disclosed |
| EP-0389189-A2 | Diazepine antiallergy agents | Pfizer Limited (GB) | 1990-09-26 | — | — | EP | disclosed |
| EP-0359499-A2 | Fluoro substituted benzocycloheptapyridine compounds, compositions and methods of use as antihistaminic compounds | SCHERING CORPORATION (US) | 1990-03-21 | — | — | EP | disclosed |
| EP-0187284-A2 | Process for the preparation of N-tert. alkyl amides of pyridine-carboxylic acids | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |
| US-4496736-A | ALKALINE HYDROLYSIS OF ALKYLACRBOXYLIC AMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-29 | — | — | US | disclosed |
| EP-0068219-B1 | PROCESS FOR THE SIMULTANEOUS PREPARATION OF CARBOXYLIC ACIDS AND N-TERT,-ALKYL AMINES | BAYER AG (DE) | 1984-08-29 | — | — | EP | disclosed |
| EP-0068219-A1 | Process for the simultaneous preparation of carboxylic acids and N-tert,-alkyl amines | BAYER AG (DE) | 1983-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230278958-A1 | TRICYCLIC HETEROCYCLES | YAP1, TERF2IP, TEAD1 | ALDH1A1 3813/4885KDM4E 2608/4885HTT 2473/4885 |
| US-20230174538-A1 | Tricyclic heterocycles | YAP1, TEAD1, TERF2IP | ALDH1A1 3857/4885KDM4E 2269/4885HTT 2092/4885 |
| US-20230226062-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | CD274, PDCD1, PDCD1LG2 | ALDH1A1 122/4885KDM4E 1970/4885HTT 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.