SCHEMBL183472

SCHEMBL183472

CCNc1nc(N)nc(N)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
GAA P10253 4/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C19 P33261 2/20 0.50
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
MCL1 Q07820 1/20 0.47
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 2/20 0.46
NFKB1 P19838 1/20 0.46
CASP3 P42574 1/20 0.46
CDK9 P50750 1/20 0.46
CDK5 Q00535 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
CDK5R1 Q15078 1/20 0.46
SENP8 Q96LD8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6835059 0.97 LMNA (0.56) LMNAGAAL3MBTL1CYP1A2CYP2C19
SCHEMBL7076660 0.95 LMNA (0.58) LMNAGAAL3MBTL1CYP1A2CYP2C19
Lindane SCHEMBL5958996 0.89 LMNA (0.48) LMNAGAAL3MBTL1CYP1A2CYP2C19
SCHEMBL8218591 0.86 LMNA (0.50) LMNAGAAL3MBTL1CYP1A2CYP2C19
SCHEMBL7770137 0.86 LMNA (0.45) LMNAGAAL3MBTL1CYP1A2CYP2C19
SCHEMBL1918163 0.84 LMNA (0.43) LMNAGAAL3MBTL1CYP1A2CYP2C19
SCHEMBL16543336 0.84 CYP1A2 (0.61) LMNAGAAL3MBTL1CYP1A2CYP2C19
SCHEMBL29400485 0.84 LMNA (0.72) LMNAGAAL3MBTL1CYP1A2CYP2C19
SCHEMBL3173616 0.84 LMNA (0.48) LMNAGAAL3MBTL1CYP1A2CYP2C19
SCHEMBL1425806 0.84 LMNA (0.72) LMNAGAAL3MBTL1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109627483-B Preparation method of melamine rigid closed-cell foam 四川金象赛瑞化工股份有限公司 2021-08-10 CN claimed
CN-111087531-A Phosphorus-nitrogen-containing flame retardant, flame-retardant polyacrylonitrile fiber and preparation method thereof 中国石油化工股份有限公司 2020-05-01 CN claimed
CN-109073973-A KrF laser negative photoresist composition with high-resolution and high aspect ratio 荣昌化学制品株式会社 2018-12-21 CN claimed
CN-106536646-A A coating composition PRC-迪索托国际公司 2017-03-22 CN claimed
WO-2009103615-A1 IMPROVEMENTS RELATING TO BENEFIT PARTICLES UNILEVER PLC (GB) 2009-08-27 WO claimed
EP-1358684-A1 ORGANIC FIELD EFFECT TRANSISTOR WITH A PHOTOSTRUCTURED GATE DIELECTRIC, METHOD FOR THE PRODUCTION AND USE THEREOF IN ORGANIC ELECTRONICS SIEMENS AKTIENGESELLSCHAFT (DE) 2003-11-05 EP claimed
US-20030168629-A1 Reactive liquid polymer crosslinking agent and process for preparation LCB WORLDWIDE, INC. 2003-09-11 US claimed
WO-2002065557-A1 ORGANIC FIELD EFFECT TRANSISTOR WITH A PHOTOSTRUCTURED GATE DIELECTRIC, METHOD FOR THE PRODUCTION AND USE THEREOF IN ORGANIC ELECTRONICS SIEMENS AKTIENGESELLSCHAFT (DE) 2002-08-22 WO claimed
WO-1995028404-A1 7,11 DISUBSTITUTED CAMPTOTHECIN DERIVATIVES, FORMULATIONS CONTAINING SUCH DERIVATIVES AND THEIR USE BIONUMERIK PHARMACEUTICALS, INC. (US) 1995-10-26 WO claimed
US-20240174563-A1 FIRE- RESISTANT OVERLAYS, FIRE-RESISTANT PANELS, AND PROCESSES FOR MAKING AND USING SAME GP BUILDING PRODUCTS SERVICES LLC 2024-05-30 US disclosed
CN-113631196-B Compounds and conjugates thereof 免疫医疗有限公司 2024-03-15 CN disclosed
CN-117624137-A Triazine skeleton small molecule heparin reversal agent and preparation method and application thereof 中国药科大学 2024-03-01 CN disclosed
CN-111213059-B Diagnostic and therapeutic methods for cancer 豪夫迈·罗氏有限公司 2024-01-09 CN disclosed
CN-117337297-A Use of SOS1 inhibitors and MTOR inhibitors for the treatment of cancer 锐新医药公司 2024-01-02 CN disclosed
US-4424284-A REACTION PRODUCT OF AN AMINOALKYL-SUBSTITUTED UREA OR THIOUREA AND AMINOPLAST CIGA-GEIGY CORPORATION (US) 1984-01-03 US disclosed
EP-0094602-A2 Smoke retardant vinyl halide polymer compositions The B.F. GOODRICH Company (US) 1983-11-23 EP disclosed
EP-0094604-A2 Smoke retardant vinyl halide polymer compositions The B.F. GOODRICH Company (US) 1983-11-23 EP disclosed
US-4363890-A Process for producing flame retardant polyamide molding resin containing melamine cyanurate TORAY INDUSTRIES, INC. (JP) 1982-12-14 US disclosed
US-4321189-A Flame retardant polyamide molding resin containing melamine cyanurate finely dispersed therein TORAY INDUSTRIES, INC. (JP) 1982-03-23 US disclosed
EP-0017925-A1 Flame retardant polyamide molding resin and process for its preparation TORAY INDUSTRIES, INC. (JP) 1980-10-29 EP disclosed