Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.45 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.45 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | IGF2R | P11717 | 2/20 | 0.40 |
| ▸ | B4GALT1 | P15291 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18349900 | 1.00 | MAPK1 (0.56) | MAPK1LGALS8LGALS3LGALS4CA1 | |
| SCHEMBL16392943 | 1.00 | MAPK1 (0.56) | MAPK1LGALS8LGALS3LGALS4CA1 | |
| SCHEMBL16392946 | 1.00 | MAPK1 (0.56) | MAPK1LGALS8LGALS3LGALS4CA1 | |
| SCHEMBL16393098 | 1.00 | MAPK1 (0.56) | MAPK1LGALS8LGALS3LGALS4CA1 | |
| SCHEMBL16393103 | 1.00 | MAPK1 (0.56) | MAPK1LGALS8LGALS3LGALS4CA1 | |
| SCHEMBL19700758 | 0.86 | MAPK1 (0.58) | MAPK1LGALS8LGALS3LGALS4CA1 | |
| SCHEMBL17860902 | 0.85 | MAPK1 (0.76) | MAPK1LGALS8LGALS3LGALS4CA1 | |
| SCHEMBL24724835 | 0.82 | MAPK1 (0.53) | MAPK1LGALS8LGALS3LGALS4CA1 | |
| SCHEMBL29172928 | 0.82 | MAPK1 (0.54) | MAPK1LGALS8LGALS3LGALS4CA1 | |
| SCHEMBL18349883 | 0.81 | MAPK1 (0.46) | MAPK1LGALS8LGALS3LGALS4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160376585-A1 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | BANK OF AMERICA, N.A. | 2016-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376585-A1 | OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION | IGF2R, IRS1, INSR | MAPK1 3890/4885LGALS8 153/4885LGALS3 483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.