⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272115 | 0.84 | — | — | |
| SCHEMBL2041262 | 0.71 | — | — | |
| SCHEMBL3044885 | 0.69 | — | — | |
| SCHEMBL3888874 | 0.67 | — | — | |
| SCHEMBL518318 | 0.67 | — | — | |
| SCHEMBL447925 | 0.67 | — | — | |
| SCHEMBL15967513 | 0.67 | — | — | |
| SCHEMBL3253791 | 0.66 | MEN1 (0.35) | — | |
| SCHEMBL518616 | 0.65 | KDM4E (0.31) | — | |
| SCHEMBL1476931 | 0.65 | MEN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6738 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324842-A | Dexamethasone weak alkaline derivative and preparation and application of preparation thereof | 沈阳药科大学 | 2024-07-12 | — | — | CN | claimed |
| CN-116410158-B | N-methyl tertiary amine selectivity C (sp3) Process for preparing tetra-substituted diene compounds by H functionalization | 青岛科技大学 | 2024-06-21 | — | — | CN | claimed |
| CN-118164980-A | Thiazole orange derivative, preparation method and application thereof | 国科温州研究院(温州生物材料与工程研究所) | 2024-06-11 | — | — | CN | claimed |
| CN-118146165-A | 2,3, 5-Trisubstituted pyrazine compound and preparation method and application thereof | 郑州大学 | 2024-06-07 | — | — | CN | claimed |
| CN-118125997-A | Pterocarpus stilbene paeonol chalcone amide derivative, preparation method and medical application thereof | 安徽中医药大学 | 2024-06-04 | — | — | CN | claimed |
| CN-118084902-A | 2-Aminothiazole pyrimidopyridone compound or pharmaceutically acceptable salt or stereoisomer, preparation method and application | 赣南师范大学 | 2024-05-28 | — | — | CN | claimed |
| US-11992499-B2 | Quinoline derivatives for use in the treatment of inflammation diseases | ABIVAX (FR) | 2024-05-28 | — | — | US | claimed |
| US-11981672-B2 | Bi-functional compounds and methods for targeted ubiquitination of androgen receptor | Montelino Therapeutics Inc. (US) | 2024-05-14 | — | — | US | claimed |
| CN-118019736-A | Molecular gel compound designed based on cereblon protein and application thereof | 标新生物医药科技(上海)有限公司 | 2024-05-10 | — | — | CN | claimed |
| WO-2023116835-A9 | MULTI-PROTEIN DEGRADATION AGENT HAVING IMIDE SKELETON | 苏州开拓药业股份有限公司 | 2024-05-02 | — | — | WO | claimed |
| US-4317922-A | [(5,6,9a-Substituted-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]alkanoic and cycloalkanoic acids and their analogs, esters, salts and derivatives | MERCK & CO., INC. (US) | 1982-03-02 | — | — | US | claimed |
| US-4316043-A | ANTIEDEMIC AGENTS | MERCK & CO., INC. (US) | 1982-02-16 | — | — | US | claimed |
| EP-0034495-A2 | Hypoglycemic guanylamidines, processes for their preparation, and pharmaceutical compositions containing them | PFIZER INC. (US) | 1981-08-26 | — | — | EP | claimed |
| US-4279912-A | ANTIALLERGENS, BRONCHODILATORS | ROUSSEL UCLAF (FR) | 1981-07-21 | — | — | US | claimed |
| US-4269837-A | HYPOGLYCEMIC AGENTS; DIABETES | PFIZER INC. (US) | 1981-05-26 | — | — | US | claimed |
| EP-0027948-A1 | Tetrahydro-fluorene compounds, processes for their preparation and pharmaceutical compositions thereof | MERCK & CO. INC. (US) | 1981-05-06 | — | — | EP | claimed |
| EP-0021580-A1 | Sulphonamide derivatives, a process for their preparation and their use as medicines | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1981-01-07 | — | — | EP | claimed |
| US-4217453-A | BACTERICIDES, ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-08-12 | — | — | US | claimed |
| US-4091115-A | ANTIDEPRESSANTS | ROUSSEL UCLAF (FR) | 1978-05-23 | — | — | US | claimed |
| US-4069064-A | Phthalocyanine formulations having high gloss, which are stabilized against recrystallization and against change of modification | BASF AKTIENGESELLSCHAFT (DT) | 1978-01-17 | — | — | US | claimed |