⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3250605 | 0.79 | — | — | |
| SCHEMBL6921840 | 0.76 | — | — | |
| SCHEMBL10832748 | 0.69 | — | — | |
| SCHEMBL738728 | 0.68 | — | — | |
| SCHEMBL2794665 | 0.67 | MEN1 (0.56) | — | |
| SCHEMBL183498 | 0.67 | — | — | |
| SCHEMBL6921851 | 0.67 | — | — | |
| SCHEMBL7438580 | 0.65 | MEN1 (0.44) | — | |
| SCHEMBL10667510 | 0.64 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL3888874 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150963-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 광주과학기술원 | 2024-07-18 | — | — | WO | claimed |
| CN-117886798-A | Substituted benzimidazoles and use thereof | 河南中医药大学 | 2024-04-16 | — | — | CN | claimed |
| CN-117794923-A | Benzodioxane compound, and preparation method and application thereof | 南京红云生物科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-116924933-A | Azobenzene compound containing isopropanolamine substructure and preparation method and application thereof | 贵州大学 | 2023-10-24 | — | — | CN | claimed |
| US-20230310428-A1 | EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-10-05 | — | — | US | claimed |
| US-20230212147-A1 | ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-07-06 | — | — | US | claimed |
| CN-116102565-A | Isolamine-containing spirochromone compound and preparation method and application thereof | 贵州大学 | 2023-05-12 | — | — | CN | claimed |
| CN-113717156-B | EGFR inhibitor, preparation method and application thereof | 南京红云生物科技有限公司 | 2023-05-09 | — | — | CN | claimed |
| EP-4166553-A1 | ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-04-19 | — | — | EP | claimed |
| CN-115916759-A | Substituted quinazoline compound, preparation method, pharmaceutical composition and application thereof | 南京红云生物科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| EP-2045237-A1 | Pyrrole compounds as inhibitors of mycrobacteria, synthesis thereof and intermediates thereto | Universita'Degli Studi di Roma "La Sapienza" (IT) | 2009-04-08 | — | — | EP | claimed |
| EP-1866283-A2 | 4-FLUOROPHENYL-DERIVATIVES OF 1-{[1,5 -BIS (4-CHLOROPHENYL) -2-METHYL-1H-PYRROL-3-YL]METHYL} -4- METHYLPIPERAZINE, SYNTHESIS PROCESS AND USES THEREOF | Universita' Degli Studi di Siena (IT) | 2007-12-19 | — | — | EP | claimed |
| WO-2006092822-A2 | 4-FLUOROPHENYL-DERIVATIVES OF 1-{[1,5 -BIS (4-CHLORO PHENYL) -2-METHYL-1H-PYRROL-3-YL]METHYL} -4- METHYLPI PΕRAZINE, SYNTHESIS PROCESS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2006-09-08 | — | — | WO | claimed |
| US-7064215-B2 | Indazole benzimidazole compounds | CHIRON CORPORATION (US) | 2006-06-20 | — | — | US | claimed |
| EP-1401831-A1 | INDAZOLE BENZIMIDAZOLE COMPOUNDS AS TYROSINE AND SERINE/THREONINE KINASE INHIBITORS | CHIRON CORPORATION (US) | 2004-03-31 | — | — | EP | claimed |
| US-20030207883-A1 | Indazole benzimidazole compounds | CHIRON CORPORATION | 2003-11-06 | — | — | US | claimed |
| WO-2003004488-A1 | INDAZOLE BENZIMIDAZOLE COMPOUNDS AS TYROSINE AND SERINE/THREONINE KINASE INHIBITORS | CHIRON CORPORATION (US) | 2003-01-16 | — | — | WO | claimed |
| US-RE33907-E | Anti-spasmodic agents having a heterocyclic ring | UNITED PHARMACEUTICALS, INC. (US) | 1992-04-28 | — | — | US | claimed |
| US-4857535-A | THIOESTERS | UNITED PHARMACEUTICALS (US) | 1989-08-15 | — | — | US | claimed |
| US-4721783-A | SMOOTH MUSCLES | UNITED PHARMACEUTICALS, INC. (US) | 1988-01-26 | — | — | US | claimed |