Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18351869 | 1.00 | SYK (1.00) | SYK | |
| SCHEMBL18351813 | 0.93 | SYK (1.00) | SYK | |
| SCHEMBL18351811 | 0.93 | SYK (1.00) | SYK | |
| SCHEMBL18351789 | 0.91 | SYK (1.00) | SYK | |
| SCHEMBL18351787 | 0.91 | SYK (1.00) | SYK | |
| SCHEMBL18351840 | 0.87 | SYK (1.00) | SYK | |
| SCHEMBL18351841 | 0.87 | SYK (1.00) | SYK | |
| SCHEMBL18351796 | 0.86 | SYK (1.00) | SYK | |
| SCHEMBL18351797 | 0.86 | SYK (1.00) | SYK | |
| SCHEMBL18351847 | 0.84 | SYK (1.00) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9533989-B2 | Substituted pyrimidine-5-carboxamides as spleen tyrosine kinase inhibitors | Ziarco Pharma Ltd. (GB) | 2017-01-03 | — | — | US | claimed |