Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18567010 | 0.92 | L3MBTL1 (0.43) | MAPTALDH1A1LMNAL3MBTL1APOBEC3A | |
| SCHEMBL18566979 | 0.90 | L3MBTL1 (0.41) | HCAR2MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL18352055 | 0.88 | HCAR2 (0.41) | HCAR2MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL18352085 | 0.86 | HCAR2 (0.42) | HCAR2ALDH1A1LMNAL3MBTL1APOBEC3A | |
| SCHEMBL18352082 | 0.86 | HCAR2 (0.42) | HCAR2MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL18352147 | 0.84 | HCAR2 (0.41) | HCAR2MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL18566998 | 0.83 | L3MBTL1 (0.41) | ALDH1A1LMNAL3MBTL1APOBEC3ACTDSP1 | |
| SCHEMBL25804277 | 0.80 | HCAR2 (0.50) | HCAR2MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL18566996 | 0.79 | CYP1A2 (0.39) | HCAR2MAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL18566997 | 0.79 | TDP1 (0.39) | MAPTALDH1A1L3MBTL1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9532968-B1 | Fumarate compounds, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2017-01-03 | — | — | US | disclosed |