Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18352165 | 1.00 | MAPT (0.46) | MAPTTLR8LIPGKCNH2KMT2A | |
| SCHEMBL15223435 | 1.00 | MAPT (0.46) | MAPTTLR8LIPGKCNH2KMT2A | |
| SCHEMBL18352188 | 0.86 | MAPT (0.46) | MAPTTLR8LIPGKMT2AMEN1 | |
| SCHEMBL15223474 | 0.86 | MAPT (0.46) | MAPTTLR8LIPGKMT2AMEN1 | |
| SCHEMBL15223467 | 0.86 | MAPT (0.46) | MAPTTLR8LIPGKMT2AMEN1 | |
| SCHEMBL16807693 | 0.82 | MAPT (0.46) | MAPTTLR8LIPG | |
| SCHEMBL16807718 | 0.79 | MAPT (0.46) | MAPTTLR8LIPGKMT2AMEN1 | |
| SCHEMBL18352160 | 0.79 | LIPG (0.44) | MAPTTLR8LIPGKCNH2KMT2A | |
| SCHEMBL15223480 | 0.79 | LIPG (0.44) | MAPTTLR8LIPGKCNH2KMT2A | |
| SCHEMBL18352174 | 0.79 | LIPG (0.44) | MAPTTLR8LIPGKCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9537110-B2 | Chalcogen-containing organic compound and use thereof | JNC CORPORATION (JP) | 2017-01-03 | — | — | US | disclosed |