Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL1835268 | 1.00 | KDM4E (0.53) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| Bicarbonate SCHEMBL1834592 | 0.92 | KDM4E (0.46) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| Bicarbonate SCHEMBL1831706 | 0.92 | KDM4E (0.46) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| Pyruvate SCHEMBL1832071 | 0.90 | KDM4E (0.46) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| Acetic Acid SCHEMBL358197 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| Propionic Acid SCHEMBL1832892 | 0.85 | FFAR3 (0.48) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| Succinic Acid SCHEMBL1833027 | 0.85 | ALDH1A1 (0.52) | KDM4EALDH1A1MEN1KMT2AATM | |
| Glycolic Acid SCHEMBL1839459 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| Succinic Acid SCHEMBL1833030 | 0.85 | ALDH1A1 (0.52) | KDM4EALDH1A1MEN1KMT2AATM | |
| Fumaric Acid SCHEMBL1833865 | 0.83 | HCAR2 (0.50) | KDM4EALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | claimed |
| US-9328220-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2016-05-03 | — | — | US | disclosed |
| US-8992798-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2015-03-31 | — | — | US | disclosed |
| US-8784686-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2014-07-22 | — | — | US | disclosed |
| US-20140187684-A1 | LIQUIDS | INNOVIA FILMS LIMITED (GB) | 2014-07-03 | — | — | US | disclosed |
| US-20110257433-A1 | LIQUIDS | THE UNIVERSITY OF YORK (GB) | 2011-10-20 | — | — | US | disclosed |
| EP-2322497-A1 | Ionic liquids comprising nitrogen containing cations | Innovia Films Limited (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-20080221361-A1 | Ionic Liquids | BIONIQS LIMITED (GB) | 2008-09-11 | — | — | US | disclosed |
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | disclosed |