Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 10/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18353688 | 0.95 | THRB (0.35) | THRBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18353820 | 0.90 | THRB (0.35) | THRBMAPTTP53HDAC1HDAC2 | |
| SCHEMBL18353826 | 0.89 | PPARD (0.37) | THRBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18353756 | 0.88 | THRB (0.38) | THRBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18353770 | 0.86 | MAPT (0.33) | THRBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18353703 | 0.84 | THRB (0.41) | THRBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL24477830 | 0.84 | THRB (0.45) | THRBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18353101 | 0.82 | THRB (0.39) | THRBMAPTKDM4ERXFP1TP53 | |
| SCHEMBL18353243 | 0.82 | THRB (0.37) | THRBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18353704 | 0.82 | THRB (0.37) | THRBMAPTKDM4ERXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902794-B2 | Curable composition, optical component and compound | FUJIFILM CORPORATION (JP) | 2018-02-27 | — | — | US | disclosed |
| US-9902794-B2 | Curable composition, optical component and compound | FUJIFILM CORPORATION (JP) | 2018-02-27 | — | — | US | disclosed |
| US-20170002124-A1 | CURABLE COMPOSITION, OPTICAL COMPONENT AND COMPOUND | FUJIFILM CORPORATION (JP) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170002124-A1 | CURABLE COMPOSITION, OPTICAL COMPONENT AND COMPOUND | CCNT1, ARPC4, NLRP1 | THRB 4156/4885MAPT 183/4885MEN1 2341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.