Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMOX | Q9NWM0 | 3/20 | 0.66 |
| ▸ | KDM1A | O60341 | 4/20 | 0.55 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 2/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18353620 | 0.89 | KDM1A (0.52) | SMOXKDM1ARCOR1MAOALCK | |
| SCHEMBL18353773 | 0.87 | KDM1A (0.66) | SMOXKDM1ARCOR1MAOALCK | |
| SCHEMBL16995667 | 0.87 | SMOX (0.72) | SMOXKDM1ARCOR1MAOALCK | |
| SCHEMBL18353486 | 0.83 | KDM1A (0.49) | SMOXKDM1ARCOR1LCKBTK | |
| SCHEMBL18353607 | 0.82 | KDM1A (0.64) | SMOXKDM1ARCOR1LCKBTK | |
| SCHEMBL18353484 | 0.81 | KDM1A (0.46) | SMOXKDM1ARCOR1LCKBTK | |
| SCHEMBL18353782 | 0.77 | KDM1A (0.45) | SMOXKDM1ARCOR1LCKBTK | |
| SCHEMBL16995650 | 0.76 | KDM1A (0.57) | SMOXKDM1ARCOR1MAOALCK | |
| SCHEMBL18353619 | 0.75 | MAPT (0.41) | SMOXKDM1ARCOR1MAOALCK | |
| SCHEMBL16995649 | 0.74 | KDM1A (0.72) | SMOXKDM1ARCOR1MAOALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | KDM1A, KDM1B, KDM3A | SMOX 41/4885KDM1A 1/4885RCOR1 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.