SCHEMBL183565

SCHEMBL183565

Clc1cc[c]s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL597085 0.63
SCHEMBL9215009 0.62
SCHEMBL385899 0.62
SCHEMBL10962257 0.62
SCHEMBL5575477 0.59
SCHEMBL1375725 0.59
SCHEMBL2039242 0.57
SCHEMBL1264108 0.57
SCHEMBL15586061 0.53
SCHEMBL193721 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5371 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344277-A Pyrrole derivative and preparation method and application thereof 山东大学 2024-07-16 CN claimed
CN-115611856-B Piperidine derivative and pharmaceutical composition, preparation method and application thereof 宜昌人福药业有限责任公司 2024-07-05 CN claimed
WO-2024115549-A1 ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2024-06-06 WO claimed
US-11987588-B2 Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto ARENA PHARMACEUTICALS, INC. (US) 2024-05-21 US claimed
CN-117986266-A 3-Cyano-6-N-heterocyclic acyl-5, 6,7, 8-tetrahydropyridine pyran derivative and preparation method and application thereof 西华大学 2024-05-07 CN claimed
CN-117903151-A 2-Amino-3-ester-6-N-methyl pyranopyridine derivative, preparation method and application thereof 西华大学 2024-04-19 CN claimed
EP-4345096-A1 PIPERIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF Yichang Humanwell Pharmaceutical Co., Ltd. (CN) 2024-04-03 EP claimed
CN-117642402-A Spiropiperidine ring derivative and pharmaceutical composition, preparation method and application thereof 宜昌人福药业有限责任公司 2024-03-01 CN claimed
CN-117642389-A Piperidine derivative and pharmaceutical composition, preparation method and application thereof 宜昌人福药业有限责任公司 2024-03-01 CN claimed
CN-117623838-A Chiral sulfoxide ester compound and preparation method thereof 贵州大学 2024-03-01 CN claimed
US-4351948-A Imidazole hydrazone derivatives G.D. SEARLE & CO. (US) 1982-09-28 US claimed
EP-0046337-A2 Triazole compounds, a process for preparing them, their use as plant and pharmaceutical fungicides and as plant growth regulators and compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-02-24 EP claimed
US-4315023-A FOR USE AS FUNGICIDES AND BACTERICIDES WESTWOOD PHARMACEUTICALS, INC. (US) 1982-02-09 US claimed
US-4197310-A ANTIARTHRITIC, ANTIINFLAMMATORY, PREVENT JOINT DETERIORATION AMERICAN CYANAMID COMPANY (US) 1980-04-08 US claimed
US-4160838-A FUNGICIDES, BACTERICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1979-07-10 US claimed
US-4071533-A Phosphoramidates and thiophosphoramidates as pesticides ABBOTT LABORATORIES (US) 1978-01-31 US claimed
US-4064132-A ANTIINFLAMMATORY AGENTS JANSSEN PHARMACEUTICA N.V. (BE) 1977-12-20 US claimed
US-4060528-A ANTIINFLAMMATORY JANSSEN PHARMACEUTICA N.V. (BE) 1977-11-29 US claimed
US-4035376-A ESTERS, AMIDES, HYDROXAMIC ACIDS, ANTIINFLAMMATORY JANSSEN PHARMACEUTICA N.V. (BE) 1977-07-12 US claimed
US-4011230-A DITHIOCARBAMATE ESTER BACTERICIDES AND FUNGICIDES AMERICAN CYANAMID COMPANY (US) 1977-03-08 US claimed