Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15436384 | 0.93 | KDM4E (0.40) | KDM4EATML3MBTL1CDK4CDK6 | |
| SCHEMBL21454370 | 0.92 | KDM4E (0.41) | KDM4EATML3MBTL1CDK4CDK6 | |
| SCHEMBL21453857 | 0.92 | KDM4E (0.41) | KDM4EATML3MBTL1CDK4CDK6 | |
| SCHEMBL15436385 | 0.91 | KDM4E (0.49) | KDM4EATML3MBTL1CDK4CDK6 | |
| SCHEMBL26329923 | 0.90 | KDM4E (0.39) | KDM4EATML3MBTL1CDK4CDK6 | |
| SCHEMBL26329926 | 0.89 | KDM4E (0.37) | KDM4EATML3MBTL1CDK4CDK6 | |
| SCHEMBL17019469 | 0.89 | L3MBTL1 (0.50) | KDM4EATML3MBTL1MAPTKMT2A | |
| SCHEMBL17248271 | 0.89 | L3MBTL1 (0.50) | KDM4EATML3MBTL1MAPTKMT2A | |
| SCHEMBL26329922 | 0.87 | KDM4E (0.43) | KDM4EATML3MBTL1CDK4CDK6 | |
| SCHEMBL10027523 | 0.87 | L3MBTL1 (0.50) | KDM4EATML3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |