Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL27732823 | 0.83 | HPGD (0.64) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL28963054 | 0.82 | KDM4E (0.69) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL2533420 | 0.82 | ALDH1A1 (0.61) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1834432 | 0.82 | POLB (0.47) | HPGDKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| Salicylic Acid SCHEMBL27675724 | 0.82 | HPGD (0.82) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL1838103 | 0.81 | KDM4E (0.45) | HPGDKDM4EALDH1A1CA12CA1 | |
| SCHEMBL1838097 | 0.81 | KDM4E (0.45) | HPGDKDM4EALDH1A1CA12CA1 | |
| Salicylic Acid SCHEMBL1835141 | 0.81 | HPGD (0.67) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL15568422 | 0.80 | ALDH1A1 (0.78) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL27871001 | 0.80 | ALDH1A1 (0.78) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | claimed |
| US-9328220-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2016-05-03 | — | — | US | disclosed |
| US-8992798-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2015-03-31 | — | — | US | disclosed |
| US-8784686-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2014-07-22 | — | — | US | disclosed |
| US-20140187684-A1 | LIQUIDS | INNOVIA FILMS LIMITED (GB) | 2014-07-03 | — | — | US | disclosed |
| US-20110257433-A1 | LIQUIDS | THE UNIVERSITY OF YORK (GB) | 2011-10-20 | — | — | US | disclosed |
| EP-2322497-A1 | Ionic liquids comprising nitrogen containing cations | Innovia Films Limited (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-20080221361-A1 | Ionic Liquids | BIONIQS LIMITED (GB) | 2008-09-11 | — | — | US | disclosed |
| EP-1948589-A1 | IONIC LIQUIDS | Bioniqs Limited (GB) | 2008-07-30 | — | — | EP | disclosed |
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | disclosed |
| WO-2007036712-A1 | IONIC LIQUIDS | BIONIQS LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |