Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31636836 | 0.84 | MAPK1 (0.43) | HSD17B10CYP2C9CYP1A2HPGDMAPK1 | |
| SCHEMBL22406694 | 0.75 | MAPK1 (0.65) | HSD17B10CYP2C9CYP1A2HPGDMAPK1 | |
| SCHEMBL1829056 | 0.72 | HSD17B10 (0.60) | HSD17B10CYP2C9CYP1A2HPGDMAPK1 | |
| SCHEMBL12402802 | 0.71 | GAA (0.48) | HSD17B10CYP2C9MAPK1TSHRPOLB | |
| SCHEMBL13024389 | 0.70 | KDM4E (0.63) | CYP2C19KDM4E | |
| SCHEMBL1834368 | 0.70 | LMNA (0.47) | HSD17B10CYP2C9HPGDMAPK1TSHR | |
| SCHEMBL3689393 | 0.69 | LMNA (0.46) | CYP2C9HPGDMAPK1TSHRPOLB | |
| SCHEMBL2586535 | 0.69 | LMNA (0.46) | CYP2C9HPGDMAPK1TSHRPOLB | |
| SCHEMBL12636227 | 0.69 | POLB (0.43) | HSD17B10CYP2C9CYP1A2HPGDMAPK1 | |
| SCHEMBL14555816 | 0.69 | TSHR (0.44) | HSD17B10CYP2C9CYP1A2HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| EP-2318374-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010012442-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | DDT, BRD9, BCL2A1 | HSD17B10 2049/4885CYP2C9 34/4885CYP1A2 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.