Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532325 | 0.88 | TSHR (0.58) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL31591533 | 0.87 | THRB (0.59) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5082921 | 0.87 | THRB (0.54) | THRBTSHRALDH1A1 | |
| SCHEMBL16803283 | 0.86 | TSHR (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL35507 | 0.86 | TSHR (0.63) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL13641684 | 0.86 | TSHR (0.51) | THRBTSHRALDH1A1LMNA | |
| SCHEMBL13572182 | 0.84 | TSHR (0.58) | THRBTSHRALDH1A1LMNA | |
| SCHEMBL19197311 | 0.83 | TSHR (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL12808955 | 0.83 | TSHR (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL16803284 | 0.82 | TSHR (0.63) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1834975-B1 | Thermosetting poly(phenylene ether) | SABIC INNOVATIVE PLASTICS IP (NL) | 2011-05-11 | — | — | EP | claimed |