Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022073 | 0.90 | RORC (0.57) | RORC | |
| SCHEMBL18359187 | 0.88 | RORC (0.55) | RORC | |
| SCHEMBL18359184 | 0.87 | RORC (0.55) | RORC | |
| SCHEMBL5022071 | 0.86 | RORC (0.60) | RORC | |
| SCHEMBL5023730 | 0.85 | RORC (0.60) | RORC | |
| SCHEMBL5022372 | 0.84 | RORC (0.57) | RORC | |
| SCHEMBL5022063 | 0.83 | RORC (0.66) | RORC | |
| SCHEMBL4559536 | 0.82 | RORC (0.56) | RORC | |
| SCHEMBL5022070 | 0.81 | RORC (0.65) | RORC | |
| SCHEMBL5022554 | 0.80 | RORC (0.62) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638014-B1 | N-SULFONYLATED TETRAHYDROQUINOLINES AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF ROR-GAMMA ACTIVITY AND THE TREATMENT OF DISEASES | LYCERA CORP (US) | 2017-01-04 | — | — | EP | disclosed |