Lactic Acid

Lactic Acid

SCHEMBL183593

CC(O)C(=O)O.CCCC(=O)O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1

The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 known ✓ O15379 1/20 0.68
HDAC1 known ✓ Q13547 1/20 0.68
HDAC2 known ✓ Q92769 1/20 0.68
HDAC8 known ✓ Q9BY41 1/20 0.68
HDAC11 known ✓ Q96DB2 5/20 0.44
PDE3A known ✓ Q14432 1/20 0.44
FFAR3 O14843 1/20 0.68
TP53 P04637 1/20 0.58
CYP1A2 P05177 1/20 0.48
AKR1B1 P15121 1/20 0.46
GPR84 Q9NQS5 7/20 0.44
PPARG P37231 7/20 0.44
PPARD Q03181 7/20 0.44
PPARA Q07869 7/20 0.44
TSHR P16473 4/20 0.44
PTPN1 P18031 3/20 0.44
TET2 Q6N021 3/20 0.44
ALDH1A1 P00352 2/20 0.44
TLR2 O60603 2/20 0.44
TDP1 Q9NUW8 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactic Acid SCHEMBL29090830 0.97 FFAR3 (0.65) FFAR3HDAC3HDAC1HDAC2HDAC8
Lactic Acid SCHEMBL10578460 0.95 FFAR3 (0.62) FFAR3HDAC3HDAC1HDAC2HDAC8
Lactic Acid SCHEMBL28965424 0.93 FFAR3 (0.59) FFAR3HDAC3HDAC1HDAC2HDAC8
Lactic Acid SCHEMBL8415566 0.91 FFAR3 (0.56) FFAR3HDAC3HDAC1HDAC2HDAC8
Lactic Acid SCHEMBL21464736 0.91 FFAR3 (0.56) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL4578587 0.89 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL8908724 0.89 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Lactic Acid SCHEMBL27902377 0.89 FFAR3 (0.54) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL17962930 0.87 FFAR3 (0.65) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL2872540 0.86 FFAR3 (0.72) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148723-A1 MYCOBACTERIUM TUBERCULOSIS COMPOSITIONS AND METHODS PZA INNOVATION LLC 2024-05-09 US claimed
CN-115745946-B Low-temperature preparation method of glycolide and lactide 中国科学院长春应用化学研究所 2024-03-26 CN claimed
CN-115650948-B Preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-12-19 CN claimed
CN-115745946-A Low-temperature preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-03-07 CN claimed
CN-115650948-A Preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-01-31 CN claimed
CN-216571712-U Plate-frame filter for butyric acid-lactic acid composite liquid 天津荣利生物科技发展有限公司 2022-05-24 CN claimed
EP-2557939-B1 COMPOSITIONS FOR ANIMAL FEED COMPRISING A BUTYRATE SALT SANLUC INTERNAT NV (BE) 2015-04-15 EP claimed
EP-2557939-A1 ANIMAL FEED FORMULATIONS COMPRISING BUTYRATE SALT Sanluc International NV (BE) 2013-02-20 EP claimed
US-20130034629-A1 ANIMAL FEED FORMULATIONS COMPRISING BUTYRATE SALT SANLUC INTERNATIONAL N.V. (BE) 2013-02-07 US claimed
WO-2011128871-A1 ANIMAL FEED FORMULATIONS COMPRISING BUTYRATE SALT SANLUC INTERNATIONAL NV (BE) 2011-10-20 WO claimed
CN-116284713-B Acetylated lactate flame retardant plasticizer containing phosphaphenanthrene group, and preparation method and application thereof 常州大学 2025-05-06 CN disclosed
CN-118742687-A Method for controlling the content of volatile fatty acids in pulp 索理思科技开曼公司 2024-10-01 CN disclosed
CN-118452168-A Hexagon essence and preparation method and application thereof 上海熙美源实业有限公司 2024-08-09 CN disclosed
EP-3897187-B1 RUMEN PROTECTED MATRIX FOR ANIMAL FEED, USE AND PROCESS BUNGE LODERS CROKLAAN B V (NL) 2024-06-26 EP disclosed
CN-115745946-B Low-temperature preparation method of glycolide and lactide 中国科学院长春应用化学研究所 2024-03-26 CN disclosed
EP-0969869-A2 COMPOSITIONS COMPRISING AN INDUCING AGENT AND AN ANTI-VIRAL AGENT FOR THE TREATMENT OF BLOOD, VIRAL AND CELLULAR DISORDERS Perrine, Susan P. (US) 2000-01-12 EP disclosed
CN-1216618-A Photoresist compositions comprising polycyclic polymers with acid labile pendant groups GOODRICH CO B F (US) 1999-05-12 CN disclosed
CN-1201447-A Butyrate prodrugs of lactic acid VERTEX PHARMA (US) 1998-12-09 CN disclosed
US-5780451-A COMPRISING MIXTURE OF UNSATURATED FATTY ACID-CONTAINING OILS AND INDIGESTIBLE CARBOHYDRATE WHICH IS METABOLIZED TO FATTY ACIDS WITHIN COLON ABBOTT LABORATORIES (US) 1998-07-14 US disclosed
WO-1998004290-A2 COMPOSITIONS COMPRISING AN INDUCING AGENT AND AN ANTI-VIRAL AGENT FOR THE TREATMENT OF BLOOD, VIRAL AND CELLULAR DISORDERS PERRINE SUSAN P (US) 1998-02-05 WO disclosed