Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HRAS | P01112 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576696 | 0.83 | TSHR (0.46) | TSHRNPC1RAB9AIDO1AGXT | |
| SCHEMBL23015788 | 0.79 | TSHR (0.39) | TSHRNPC1RAB9AIDO1AGXT | |
| SCHEMBL9100722 | 0.75 | TSHR (0.46) | TSHRNPC1RAB9AIDO1AGXT | |
| SCHEMBL689184 | 0.75 | NPC1 (0.48) | TSHRNPC1RAB9AIDO1AGXT | |
| Bromide SCHEMBL38656295 | 0.73 | NPC1 (0.47) | TSHRNPC1RAB9AIDO1AGXT | |
| SCHEMBL8947459 | 0.73 | TSHR (0.44) | TSHRNPC1RAB9AIDO1AGXT | |
| Hydrochloric Acid SCHEMBL6944557 | 0.73 | NPC1 (0.47) | TSHRNPC1RAB9AIDO1AGXT | |
| Ammonia Solution, Strong SCHEMBL28447660 | 0.73 | NPC1 (0.47) | TSHRNPC1RAB9AIDO1AGXT | |
| SCHEMBL21776500 | 0.73 | NPC1 (0.47) | TSHRNPC1RAB9AIDO1AGXT | |
| SCHEMBL27952705 | 0.73 | NPC1 (0.47) | TSHRNPC1RAB9AIDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017004525-A1 | DIABETES AND METABOLIC SYNDROME TREATMENT WITH A NOVEL DUAL MODULATOR OF SOLUBLE EPOXIDE HYDROLASE AND PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2017-01-05 | — | — | WO | disclosed |