Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338689 | 0.89 | HPGD (0.36) | PDGFRBMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL340641 | 0.82 | EDNRA (0.35) | MAPTALDH1A1KDM4ENPC1MEN1 | |
| SCHEMBL10267983 | 0.81 | ALDH1A1 (0.36) | PDGFRBMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL10200331 | 0.76 | MAPT (0.35) | MAPTALDH1A1KDM4ENPC1MEN1 | |
| SCHEMBL339698 | 0.74 | MEN1 (0.42) | MAPTALDH1A1KDM4ENPC1MEN1 | |
| SCHEMBL339931 | 0.74 | MEN1 (0.41) | MAPTALDH1A1KDM4ENPC1MEN1 | |
| SCHEMBL2795234 | 0.72 | NPC1 (0.40) | MAPTALDH1A1KDM4ENPC1MEN1 | |
| SCHEMBL2798406 | 0.70 | NPC1 (0.40) | MAPTALDH1A1KDM4ENPC1MEN1 | |
| SCHEMBL10200098 | 0.67 | ALDH1A1 (0.37) | MAPTALDH1A1KDM4ENPC1MEN1 | |
| SCHEMBL10262788 | 0.66 | ALDH1A1 (0.38) | MAPTALDH1A1KDM4ENPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3112348-A1 | SYNTHESIS AND ANTICANCER ACTIVITY OF ARYL AND HETEROARYL-QUINOLIN DERIVATIVES | Tairx, Inc. (TW) | 2017-01-04 | — | — | EP | disclosed |