Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16024506 | 0.85 | SPHK2 (0.44) | SPHK2HDAC3F10KMT2ASMN1; SMN2 | |
| SCHEMBL24346423 | 0.84 | SMN1; SMN2 (0.49) | SPHK2HDAC3F10KMT2ASMN1; SMN2 | |
| SCHEMBL19119536 | 0.83 | F10 (0.43) | SPHK2F10KMT2ASMN1; SMN2HPGD | |
| SCHEMBL18923749 | 0.83 | F10 (0.47) | SPHK2F10KMT2ASMN1; SMN2HPGD | |
| SCHEMBL24570793 | 0.80 | F10 (0.41) | SPHK2HDAC3F10KMT2AALDH1A1 | |
| SCHEMBL24370728 | 0.80 | MAOB (0.44) | SPHK2HDAC3F10KMT2ASMN1; SMN2 | |
| SCHEMBL18685480 | 0.79 | TDP1 (0.49) | F10KMT2ASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL18736302 | 0.79 | SPHK2 (0.51) | SPHK2HDAC3F10KMT2ASMN1; SMN2 | |
| SCHEMBL26167876 | 0.78 | LOX (0.43) | SPHK2HDAC3F10KMT2ASMN1; SMN2 | |
| SCHEMBL891480 | 0.77 | ALDH1A1 (0.64) | KMT2ASMN1; SMN2HPGDRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964624-B1 | RHODAMINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LTD (GB) | 2017-01-04 | — | — | EP | disclosed |