SCHEMBL18360498

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18354523	0.82	NPC1 (0.59)	CA12CA1CA2CA9MAOB
	SCHEMBL5415117	0.81	MAOB (0.80)	MAOBNPC1RAB9AROCK2MAP4K4
	SCHEMBL1823677	0.78	MAPK1 (0.49)	CA12CA1CA2CA9
	SCHEMBL2282888	0.77	CA1 (0.70)	CA12CA1CA2CA9PRSS1
	SCHEMBL2276212	0.77	CA1 (0.73)	CA12CA1CA2CA9PRSS1
	SCHEMBL16863691	0.75	CA1 (0.67)	CA12CA1CA2CA9PRSS1
	SCHEMBL2287068	0.75	CA1 (0.74)	CA12CA1CA2CA9NPC1
	SCHEMBL5381378	0.75	NPC1 (0.76)	MAOBNPC1RAB9AROCK2MAP4K4
	SCHEMBL2278817	0.75	CA1 (0.78)	CA12CA1CA2CA9PRSS1
	SCHEMBL2280424	0.75	CA1 (0.78)	CA12CA1CA2CA9PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.